Butyric acid of the future

For decades butyric acid has been used in the feed industry to improve gut health and animal performance. Several new generations have been introduced to improve the handling of the product and its performance since the first trials were done in the 80s (fig. 1).


Development of butyric acid as feed additive
Fig. 1    Development of butyric acid as feed additive


Today the market is dominated by well protected butyric acid. Feed producers working with these additives have no problems with smell issues and the effect of the additives on gut health and performance is better. The problem with conventional coated products is however the low concentration of butyric acid. Coated salts usually contain 25-30% butyric acid, which is very low.

The latest development in butyric acid based feed additives is the development of ProPhorce SR: glycerol esters of butyric acid. These triglycerides of butyric acid can naturally be found in milk and honey. They are the most efficient source of protected butyric acid with a concentration of butyric acid up to 85%. Glycerol has room to have three butyric acid molecules attached to it through so called 'ester bonds'. These powerful connections are present in all triglycerides and they can only be broken by specific enzymes (lipase). In the crop and stomach the tributyrin stays intact and in the intestine where pancreatic lipase is readily available the butyric acid is released.


Comparison between coated salts of butyric acid and ProPhorce™ SR

Fig. 2    Comparison between coated salts of butyric acid and ProPhorce™ SR.


The technique of esterifying butyric acid has proven to be the most efficient way of creating odorless butyric acid that is released where you want it: in the gut. The differences with coated salts are listed in fig. 2.

At the 20th ESPN in Prague, a comparative study was presented on the effect of 2 different butyric acid based additives in broilers. The trial was performed at ADAS research center in the UK in 2014. They compared a coated sodium salt (with 68% coating) with ProPhorce™ SR 130 (55% butyric acid). 720 Coss308 male chicks were divided into 3 groups, with 12 pens of 20 birds per group. To mimic commercial conditions as closely as possible, dirty litter was added after parasitological, bacterial and viral pathological evaluation. The results are listed in fig. 3.


Dosage (kg/ton feed





0 – 0 – 0 



 ProPhorce™ SR

 0,5 - 0,25 - 0,25



 Coated Na- Butyrate

1 – 0,5 – 0,5



Fig. 3 Results of 2 different butyric acid sources on broiler performance. a,b means followed by different letters are significantly different P < 0,05

The results show that the addition of ProPhorce™ SR at isobutyric dose levels mentioned above improve FCR, ADG and final weight in comparison with control and do not differ from coated butyric acid treatment at isobutyric dosage.

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